Androgen Responsive Genes in Prostate Cancer

This book is intended for individuals interested in cancer endocrinology and medical and healthcare professionals involved in prostate cancer research.

Androgen Responsive Genes in Prostate Cancer

Androgen Responsive Genes in Prostate Cancer

Androgens and androgen receptors (AR) play critical roles in the development and progression of prostate cancer, the most frequently diagnosed cancer and second leading cause of cancer death in US males. AR is an androgen-dependent DNA-binding transcription factor that regulates the expression of androgen-responsive genes. Identification and characterization of androgen-responsive genes provide insights into the cellular mechanisms of androgen action and may lead to new approaches in diagnosis, prognosis, prevention and/or treatment of prostate cancer. This volume provides critical information from well respected experts in the field. Some of the exciting topics include the new understanding of mechanisms underlining the regulation of androgen-responsive gene expression, and functions of various androgen-responsive genes in biological processes essential in carcinogenesis including cell growth, angiogenesis, and epithelial-to-mesenchyme transition (EMT). Other important aspects addressed are the current and potential clinic applications of knowledge on androgen-responsive gene regulation and function. This book is intended for researchers, scientists, faculty, and advanced graduate students with an interest in androgen action and prostate cancer.​

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Androgen-Responsive Genes in Prostate Cancer
Language: en
Pages: 348
Authors: Zhou Wang
Categories: Medical
Type: BOOK - Published: 2013-02-16 - Publisher: Springer Science & Business Media

Androgens and androgen receptors (AR) play critical roles in the development and progression of prostate cancer, the most frequently diagnosed cancer and second leading cause of cancer death in US males. AR is an androgen-dependent DNA-binding transcription factor that regulates the expression of androgen-responsive genes. Identification and characterization of androgen-responsive
Androgen Action in Prostate Cancer
Language: en
Pages: 826
Authors: Donald Tindall, James Mohler
Categories: Medical
Type: BOOK - Published: 2009-04-20 - Publisher: Springer Science & Business Media

Androgens are critical regulators of prostate differentiation and function, as well as prostate cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the androgen receptor (AR), a nuclear receptor transcription factor. Historically, the gene
Cancer Research
Language: en
Pages:
Authors: Donald Tindall, James Mohler
Categories: Cancer
Type: BOOK - Published: 2007 - Publisher:

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Understanding the Molecular Determinants of Prostate Tumorigenesis: Androgen Receptor's Requirement for Histone Deacetylases and the Role of Recurrent ETS Fusion
Language: en
Pages: 240
Authors: Jin Xu
Categories: Cancer
Type: BOOK - Published: 2008 - Publisher:

Books about Understanding the Molecular Determinants of Prostate Tumorigenesis: Androgen Receptor's Requirement for Histone Deacetylases and the Role of Recurrent ETS Fusion
Hormones and Growth Factors in Development and Neoplasia
Language: en
Pages: 461
Authors: Robert B. Dickson, David S. Salomon
Categories: Medical
Type: BOOK - Published: 1998-05-06 - Publisher: Wiley-Liss

Hormones and Growth Factors in Development and Neoplasia Edited by Robert B. Dickson, Lombardi Cancer Research Center, Georgetown University David S. Salomon, Laboratory of Tumor Immunology and Biology, National Cancer Institute, NIH The study of hormones is critical to our understanding of developmental aberrations leading to cancer, and the discovery

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